Certainly mate.
I've driven lots of this model and speaking purely personally, £ for £ it's one of the nicest cars around to drive, and as you might read later with today's review of a BMW 420i, the E220 is - in my opinion - the far superior two-door coupe.
All the E-Class range are extremely well engineered - as you would expect from Mercedes-Benz - and build quality is superb The E220 is very comfortable to drive and has excellent performance... and for a convertible doesn't suffer any undue wind noise from having a soft top.
Steering is precise and the suspension makes for a really smooth drive.
Acceleration, even from the diesels, and the brakes - when needed - are both excellent.
The diesel models are as quiet as the petrol versions and return excellent miles per gallon, and as I will repeatedly say, if you drive to within 10% excess of the legal speed limits, most cars deliver their best mpg figures - the E220d easily 50+ and on a long motorway run 60+ is more than achievable.
Next time I drive one, I'll get a couple of photos to add to this brief review