I'm pretty sure that La Liga head to head counts when teams end up equal on points so it looks like anything could happen by the end of play. Little Eibar look like escaping anyway and La Coruna have just dropped into the bottom 3.
Granada hold the advantage over DLC and even conceding a goal to draw level would save them. If, on the other hand, Almeria get a goal to go back to 35 points they will tie with Granada and Eibar. As far as I can see this means Granada go down as the 3 team head-to-head is Almeria 7, Eibar 5 and Granada 3 points.
At the top end if Atletico lose and Valencia win this puts Valencia in 3rd place. Sevilla can leap over Valencia if they score now.