I'm very curious about how they will approach games this season. Last year they went hell-for-leather in the first 30 min of a game, with that sort of tempo impossible to maintain for 90 min. Usually they scored in that period, and could sit back and counterattack. However, when they failed to score within the first half hour, their record was abysmal. Without Suarez they probably won't be scoring in that first third of the the match 80% of the time.
Also think teams will have learned a lesson from watching us, Arsenal and Spurs against them and not foolishly play a high line.