I used to live in Lille for a couple of years - it's a great day/night out.
It's a 45 minute drive from Calais or a 75 minute train from London (Eurostar- direct).
It's also a 50 minute train from Paris CDG Airport (direct) and a 70 minute train from Brussels (direct)
Brand new stadium (open for it's second season), 50,000 seater, retractable roof, awesome place. and they never fill it.
LOSC did the cup/league double a few years ago, but then they lost Eden Hazard, Debuchy, Cabaye, Gervinho and basically the whole team and have been rubbish ever since.
Joe Cole was an emergency loan the summer after because they had noone of quality, Solomon Kalou is their striker these days.