At the risk of sounding silly, we absolutely could.
What the 14 would need to do is get in contact with the football league. Create a new division between the Championship and the Premier League. Call it Division 1, and have it ran by the Football League. Promote 10 teams from the championship to make it a 24 league team, then stop promotion and relegation from the Premier League.
Rebrand the rest of the Football League pyramid. So the Championship becomes Division 2, League One becomes Division 3, and League Two becomes Division 4. The FA and UEFA then give the European spots to Division 1 places. Lastly, renegotiate the TV deals. Likely taking a bit of hit, but that would just even the gap between the 14 ex Premier League teams and 10 promoted Championship teams.
Then just leave the scab six to rot in the Premier League. There would be absolutely nothing any of them could do about it. And they would finally have thier closed league. If they want to re-enter the football league, then they start from the bottom. Like Wimbledon had to do.
I'm sure I'm missing some finer details, but that would be ideal to me