You can't, or at least you shouldn't be able to, pick and choose what games you want to play. How can you have a squad to put out against a Premier League outfit in a cup competition but not play in the league a few days later?
At has been discussed, they don't have many COVID cases at all, they have a lot of injuries and players at Afcon but since when has a team ever been able to cancel games before on that basis?
If they don't want to play (want being the key word because they can obviously play if they were forced to) then they should be made to forfeit the match.