Of course. That is the key question. There's no "right" or "wrong" answer in this.
My view is, there are 6 attacking positions to be filled after the back 4. They have the onus to create. I happen to think;
1) Keeping James fit
2) Getting Richarlinson back to form
3) Getting DCL fully
Will have more impact on the team than whether Digne plays left back or left midfield, or Coleman replaces Holgate (I see Coleman as essentially quite a defensive fullback now too).
My own view (and others are welcome to contradict me) our best chance to get top 4 is to do is with solidity. It may not be Serie A, but 3 goals (2 in open play) in 6 games conceded is very solid, over a prolonged period. That is a better chance than going for attacking shoot outs. If we can concede 20 or less from the next 20 games, we are in with a great opportunity. James will find ways to score goals, as will DCL. We will score goals off set plays (we could have got 3 in the last 10 minutes yesterday) given the height of the team. If Richarlinson can hit a sweet spell, he is also a good finisher (he's just not carrying the ball right)
Thats just my view though. It sounds logical to me, but as you say you are justifying playing arguably the best left back in the world out of position to accomodate a right footed centre back.