Adrenaline features as one of the drugs banned by the World Anti-Doping Agency (WADA).
There has been considerable interest expressed in the use of drugs by athletes to improve performance. As the physiological secretion of adrenaline into the bloodstream in response to stress, fright or physical exercise undeniably affects performance, it is not surprising that a number of categories of drugs that are used by some athletes to alter performance have their effects on the adrenergic system.
β2-Adrenoceptor agonists are used therapeutically for the treatment of asthma and exercise-induced asthma owing to their potent bronchodilator activity. However, the use of β2-AR agonists by athletes is prohibited under the World Anti-Doping Agency (WADA) World Anti-Doping Code, with the exception of formoterol, salbutamol, salmeterol and terbutaline, when administered by inhalation if the athlete has been granted a therapeutic use exemption (The World Anti-Doping Code—The 2008 Prohibited List International Standard). Actions and potential actions of β-agonists that could lead to the enhancement of performance in sport include bronchodilation, anabolic and anti-inflammatory actions.