ok,
@barneygumble, from someone very familiar with SD, just there last week:
I'm very happy to help! Downtown and North Park (about 5-10min from downtown) are your best bets since everywhere else, the breweries are a bit spread out.
The ones I like downtown are:
Amplified Ale Works - they just opened and are doing their Grand Opening in two weeks.
1429 Island Ave, San Diego, CA 92101
Stone Brewing - this location is literally RIGHT NEXT to the baseball stadium. It's brews only, no food, but the beer list is full of the Stone products including the draft only varieties
795 J St, San Diego, CA 92101
The Neighborhood - not a brewery, but they have the best beer list downtown in my opinion and their food is really good. They get bonus points for the craft cocktail speakeasy in the back (called Noble Experiment - reservations required and you can book one week out and they fill up FAST, go to the website for details
https://nobleexperimentsd.com/)
777 G St, San Diego, CA 92101
Duck Foot - great brews, the place hasn't opened yet but should be solid once they are opened which should be soon. 550 Park BlvdSan Diego, CA 92101
Half Door Brewing - they serve primarily English style ales with some So Cal influence (aka HOPS) The brewery is also a restaurant and the decor is pretty fun.
903 Island Ave, San Diego, CA 92101
The breweries in North Park are:
Rip Current - LOVE this place. They brew a wide variety and do them VERY well
4101 30th St, San Diego, CA 92104
Fall Brewing - these guys are the epitome of So Call beer. Punk rock, gear heads who love beer.
4542 30th St, San Diego, CA 92116
Modern Times - They are a big brewery and have a few locations all the way up to LA. But their stuff is solid and the North Park location is just flat out cool.
3000 Upas St, San Diego, CA 92104
Belching Beaver - home to probably the best peanut butter stout on the planet. They do a Mexican chocolate one which is pretty awesome too ("viva la beaver")
4223 30th St, San Diego, CA 92104
If they really want a taste of San Diego, they should consider a beer tour. It is totally worth it, especially if you have a small group. We used this one in the past
https://brewerytoursofsandiego.com/
Finally, something fun to do in downtown is one of the beer bike tours. They don't necessarily hit all of the breweries but they will go by one or two and a couple local bars as well. You can go solo and join a group or bring your own group. Good times.
https://socialcycleca.com/