Well not really.
All that'd tell me is one of two things:
a. A significant player (Baines or Fellaini) is on his way out.
b. The board is that stupid that they'd sell Heitinga without having a replacement lined up.
They're our only sellable assets. Nobody else would generate any money. Nobody is gonna pay 10m for Barkley, Jagielka will be staying for probably the rest of his career, Howard isn't worth a carrot, Jelavic and Anichebe are worth a fiver a pop. Mirallas would fetch a bit, but he won't leave for another few seasons at least.
Other teams use new managers to make a statement of intent with their signings.
We end up with Alcatraz and Kone from relegated Wigan.